Brain imaging predictors and the international study to predict optimized treatment for depression: study protocol for a randomized controlled trial

Table 2 Cross-site validation of the T1 SPGR anatomical protocol

Intra-class correlation	Stanford scan 1	Stanford scan 2	Sydney scan 1	Sydney scan 2
Stanford scan1	1.0
Stanford scan 2	0.999	1.0
Sydney scan1	0.996	0.996	1.0
Sydney scan 2	0.997	0.996	0.996	1.0
Mean gray matter volume (mm³)	7,175 ± 5,527	7,198 ± 5,552	7,193 ± 5,620	7,226 ± 5,668

Intra-class reliability coefficients for volumetric data estimated for 68 brain gray matter regions using the T1 SPGR MRI protocol, using repeat scans done at the Stanford and Sydney site magnetic resonance scanners. Data show that inter-site scan reliability (for example, Stanford scan 1 - Sydney scan 1) is high and on the same comparative level as within-site scans (for example, Sydney scan 1 and Sydney scan 2). The mean (+ SD) for gray matter volume across the 68 brain regions for each scan is also listed.
MRI Magnetic resonance imaging, SD Standard deviation, SPGR Spoiled gradient recalled.

ISSN: 1745-6215