· Readmission: 30-day, 3-month, 6-month, 1-year | · Inhaled β-agonist therapy is required no more frequentlythan every four hours |
· Number of hospital admissions | |
· Interval before next admission | · Patient, if previously ambulatory, is able to cope with basic needsin his/her situation, in usual environment |
· Frequency and severity of exacerbation | |
· Mortality: in-hospital, 30-day, 3-month, 6-month, 1-year | · Patient is able to eat and sleep without frequent awakening by dyspnoea |
· Survival: 1-year | |
· Length of stay (LOS) | · Patient has been clinically sTable for 12 to 24 hours |
· Level of understanding of inhaler therapy | · Last measure of arterial blood gases (ABGs) were accepTableaccording to condition of the patient |
· Compliance with home oxygen therapy | |
· Performance of physical exercise | · Patient and/or home caregiver fully understands correct use of therapy:oral medication therapy, inhaler therapy, oxygen therapy if homeoxygen therapy |
· Smoking status: 30-day, 3-month, 6-month, 1-year | |
· Symptoms of anxiety and depression | |
Patient, family, and physician are confident that the patient canmanage successfully | |
· Health-related quality of life (HRQL): symptoms, disability,morbidity and quality of life; psychological well-being) | · Lung function parameters: forced expiratory volume in onesecond (FEV1), forced vital capacity (FVC), inspiratory capacity |
· Health status | |
· Quality-adjusted life expectancy measure (QALY) anddisability adjusted life years (DALY) | |
· Quality of sleep | |
· Functional capacity | · Nutritional status |
· Exercise capacity | · Patients’ perception of coordination between hospital andhome healthcare |
· Physical performance: 6-minute walking distance (6-MWD),20-MWD, shuttle walk test, maximum workload, treadmill time,maximum oxygen uptake, quadriceps strength, hand grip force,maximal inspiratory mouth pressure | |
· Patient satisfaction with therapy and care | |
· Adverse event related to regular clinical examination by an investigator | |
· Severity of breathlessness: dyspnea, symptoms at rest andduring exercise | · Cost of illness (COI) analysis |
· Absenteeism |