Table 2 Sample size calculation
| Â | Mean (SD) | Detectable difference | Calculated sample size (per arm) |
|---|---|---|---|
Loss of volume of medial tibial cartilage | 4.5% ± 6.5% | 2.16% | 143 |
Increase in medial tibial bone area | 1.6% ± 2.8% | 0.9% | 153 |
Incidence of knee cartilage defects | 80% | 15% | 136 |